Research is a very strange thing.  The topics selected by researchers do not seem to have any direction.  They are selected at the whim of the researcher who decides what question needs to be addressed.  Consequently, it is sometimes difficult … Continue reading

For many years, conditions were treated and doctors did not really know whether they were achieving anything. Doctors tried to achieve good glycaemic control in people with diabetes without really knowing whether anything was being achieved. It was not until … Continue reading

“An MP’s Committee has warned that drugs companies routinely withhold results of clinical trials from doctors, leaving them poorly informed about how to treat patients” This report from the Public Accounts Committee arose as a result of the Department of … Continue reading

If ever there was a “wonder drug”, then a statin would have a good chance of being called by such a name.  New guidance from America suggests that even more people would benefit from taking a statin than ever before. … Continue reading

The recent impact of the long trial on the benefits of HRT has again rasied the whole  question of clinical trials. The report: “Schierbeck LL, Rejnmark L, Tofteng CL et al, Effect of hormone replacement therapy on cardiovascular events in … Continue reading

Few if any things have had such a pharmaceutical roller-coaster ride than Hormone Replacement Therapy (HRT).  Let’s just look at the last 15 years. In the mid- to late nineties, HRT was the flavour of the month.  Eminent writers, such … Continue reading

A pressure to reduce overall drug costs had to come as part of the government drive to reduce overall spending.  It is hardly surprising that one of the pressures should come in the field of insulin when the annual spend … Continue reading

Today I am remembering someone whose name I was not aware of until today.  His contribution to the world was the virtual reinventing of the way that medical research was performed.  His name was Paul Meier, whose obituary was published … Continue reading

We make no apology for coming back to the subject of evidence again. This is an age of evidence-based medicine. And this makes a lot of sense. There seems little point in doing something unless there is firm evidence that … Continue reading