The safety and efficacy of SGLT2 inhibitors

Since the SGLT-2 inhibitors have been launched there have been studies that have suggested potential concerns such as ketoacidosis and amputation and those that have demonstrated positive benefits on cardiovascular outcomes. This meta-analysis of the drugs …

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Gain Your Inhibitions

Today, we enter happily into the secret world (as far as NICE is concerned) of SGLT2 inhibitors. These clever drugs increase glucose excretion by the kidney thereby reducing blood glucose levels. When manufacturers produce new drugs …

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Me Too!

As long as manufactured goods have been around, “me-too” preparations have been around.  When a successful thing is introduced, competitors produce a similar one, but sufficiently different not to infringe patent laws. When Renault introduced the …

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Have a Heart

For many years, conditions were treated and doctors did not really know whether they were achieving anything. Doctors tried to achieve good glycaemic control in people with diabetes without really knowing whether anything was being achieved. …

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Statins Again

It is difficult to remember any time in the past when the British Medical Journal has withdrawn information in any articles it has published and yet this has now happened in the case of two articles …

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Don’t Fall For It!

We often seem to end up in Primary Care talking about what are often known as “trade-offs”. That is balancing the beneficial effects of drugs against possible harms due to side-effects. There are even ways of …

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